Nat. Prod

Recent Papers/Articles

Recent advances in engineering nonribosomal peptide assembly lines

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Hot off the press

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Biosynthesis of polyketides by trans-AT polyketide synthases

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Dereplication, sequencing and identification of peptidic natural products: from genome mining to peptidogenomics to spectral networks

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The use of isolated natural products as scaffolds for the generation of chemically diverse screening libraries for drug discovery

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Photo-cross-linked small-molecule affinity matrix as a tool for target identification of bioactive small molecules

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Natural products-prompted chemical biology: phenotypic screening and a new platform for target identification

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Marine natural products

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Calyculin: Nature's way of making the sponge-derived cytotoxin

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I only have eye for ewe: the discovery of cyclopamine and development of Hedgehog pathway-targeting drugs

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Synthetic approaches towards alkaloids bearing [small alpha]-tertiary amines

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Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?

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Discoveries, target identifications, and biological applications of natural products that inhibit splicing factor 3B subunit 1

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Neurite outgrowth enhancement by jiadifenolide: possible targets

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Integrated profiling methods for identifying the targets of bioactive compounds: MorphoBase and ChemProteoBase

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Advances in identification and validation of protein targets of natural products without chemical modification

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Strategies for target identification of antimicrobial natural products

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Peloruside A: a lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease

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Natural products discovery needs improved taxonomic and geographic information

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Target identification by image analysis

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